Rabbit Anti-Dengue Virus Type 3
Catalog Number LS-C57802
Purity Affinity purified
Applications ELISA, IF, IHC-P, WB
Conjugate/Tag Unconjugated
Antigen Dengue Virus
Isotype IgG2a
Host Mouse
Clone Dengue 1-11(3)
Format PBS, 0.05% sodium azide
Reactivity Virus
Clonality Monoclonal
Quantity 0.25 mg
Dengue virus 3 (DENV-3) is one of four dengue virus serotypes, responsible for causing dengue fever. A member of the flaviviruses, DENV-3 is a spherical, enveloped single stranded RNA virus. Its small genome size of 11 kilobases encodes only three structural and seven nonstructural proteins. Part of its life cycle is spent inside the Aedes mosquito host, before infecting the human bloodstream. Dengue virus 3 antibodies are provided by a variety of antibody suppliers.
Recognizes all four dengue virus serotypes (DEN-1, DEN-2, DEN-3 and DEN-4) of the genus Flavivirus. The dengue virus is responsible for the tropical and sub-tropical diseases, dengue (DF) and dengue hemorrhagic fever (DHF), transmitted to individuals through the bite of the Aedes mosquito.
The global distribution of dengue is expanding and comparable to that of malaria, with symptoms ranging from a mild viral syndrome of high fever, rash, headache, fatigue and muscle and joint pain, to the more severe and sometimes fatal DHF.
Each dengue virus serotype is antigenically distinct, such that infection only provides an individual with immunity to the causative serotype, with the possibility of further infection by a different serotype or even multiple serotypes. Detects an anti-E/envelope specific band of 61kD under reducing conditions in Western blotting. A weak secondary band of 80kD may also be apparent