Peripherin Antibody
Biological source
rabbit
Quality Level
100
Conjugate
unconjugated
Antibody form
affinity isolated antibody
Antibody product type
primary antibodies
Clone
polyclonal
Form
buffered aqueous solution
Mol wt
antigen 53 kDa
Species reactivity
human, rat
Concentration
~1 mg/mL
Anti-Peripherin antibody detects endogenous levels of total Peripherin protein.
The PRPH (peripherin) gene is mapped to human chromosome 12q13.12. This gene codes for a 57 kDa intermediate filament protein. Peripherin is predominantly expressed in the peripheral neurons.
Peripherin is known to be associated with the mechanism of organelle transport, function and positioning. It also forms an important part of the cytoskeleton. Mutation in PRPH (peripherin) is observed in amyotrophic lateral sclerosis. Peripherin participates in the elongation of motor axons. Upregulation of PRPH is noticed in neuronal injury.