Biological source

rabbit

Quality Level

100

Conjugate

unconjugated

Antibody form

affinity isolated antibody

Antibody product type

primary antibodies

Clone

polyclonal

Product line

Prestige Antibodies^® Powered by Atlas Antibodies

Form

buffered aqueous glycerol solution

Species reactivity

human

Packaging

antibody small pack of 25 μL

Cytoplasmic serine hydroxymethyltransferase or SHMT1 regulates the biosynthesis of thymidylate in mammals. SHMT1 catalyzes the conversion of serine to glycine, which also results in the formation of 5,10-methylene-tetrahydrofolate.

Rises in SHMT1 activity have been linked to increased DNA synthesis in tumors and hence SHMT1 can have cancer therapeutic implications . Anti-SHMT1 antibody is specific for SHMT1 in humans.