Anti-AXL (phosphorylated Y698, Y702
Host Animal Rabbit
Specificity Human, Mouse, Rat
Antibody Isotype IgG
Application WB, IHC-P, ELISA
Immunogen KLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of
Tyr698+Tyr702+Tyr703.
Specificity Human, Mouse, Rat
Antibody IsotypeIgG
Clonality Monoclonal
Application Notes The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
AXL is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs.
It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types.