Anti-ANP Antibody Mouse Anti Human
Species Reactivity Human, Mouse, Rat
Published species Mouse
Host/Isotype Rabbit / IgG
Class Recombinant Monoclonal
Type Antibody
Clone 17H19L1
Immunogen Peptide corresponding to human NPPA(ANP) (aa127-145)
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Protein A
Storage buffer PBS, pH 7.4
Contains 0.09% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID AB_2662340
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Pig
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.